Anti-Inflammatory Peptide • Immune Response Research • Cellular Signalling Studies
KPV (Lysine-Proline-Valine) is a naturally occurring tri-peptide derived from the Alpha-Melanocyte-Stimulating Hormone (α-MSH). In the world of research and optimization, it is highly regarded as a potent anti-inflammatory and antimicrobial agent without the typical side effects of melanocortins (like skin darkening).
Key Benefits in Research
Systemic Anti-Inflammatory: KPV works by inhibiting pro-inflammatory cytokines. It is a primary subject in studies involving IBS/IBD (Crohn’s and Ulcerative Colitis) due to its ability to soothe the gut lining.
Skin Health & Wound Healing: In dermatological research, it is studied for its ability to reduce symptoms of psoriasis and eczema, as well as its antimicrobial properties against pathogens like Staphylococcus aureus.
Mast Cell Stabilizer: It is often investigated for its role in stabilizing mast cells, making it a point of interest for research into Histamine Intolerance or Mast Cell Activation Syndrome (MCAS).
Non-Melanotropic: Unlike its parent molecule (α-MSH), KPV does not bind to the MC1R receptor, meaning it does not cause changes in skin pigmentation.
Dosing & Reconstitution
KPV is highly versatile and is often researched via subcutaneous injection, oral capsules (for gut health), or topical creams.
Subcutaneous Research Dose: Common research protocols often utilize 200mcg to 500mcg per day.
Storage & Stability
Peptides are delicate, and KPV is no exception. To maintain the integrity of the Life-OS batches, follow these guidelines:
Lyophilized Powder (Pre-mix):
Room Temp: Stable for 3–4 weeks (good for shipping).
Refrigerator (2°C–8°C): Stable for up to 24 months.
Freezer (-20°C): Stable for several years.
Reconstituted (Post-mix):
Must be refrigerated. Once mixed with BAC water, it should be used within 30–60 days.
Avoid Light: Store in a dark place or an opaque vial box to prevent UV degradation.