Thymogen is a synthetic dipeptide with the chemical structure H-Glu-Trp-OH (L-Glutamyl-L-Tryptophan). It is a short- chain, tissue-specific bioregulator peptide originally developed in the former Soviet Union as part of the Khavinson peptide series. Thymogen mimics natural thymic factors and acts as a highly selective immunomodulatory signal.
Mechanism of Action
Thymogen binds to specific receptors on immune cells (primarily T-lymphocytes, NK cells, and monocytes/macrophages) and modulates intracellular signalling pathways. It normalizes gene expression patterns involved in:
These effects result in balanced immune homeostasis, enhanced cellular immunity, reduced chronic inflammation, and accelerated recovery of immune competence after stress, infection, or age related decline.
Indications & Usage
Thymogen is used to support immune system function and resilience. It is indicated for:
Maintenance and restoration of immune competence
Assistance during periods of increased immune demand (e.g., recovery from illness, stress, or environmental exposure)
Support for age-related decline in thymic activity and T-cell function
General immune modulation and anti-aging support at the level of the immune system
Contraindications & Warnings
Do not use if you have:
Known hypersensitivity to any component of the formulation
Active autoimmune disease in acute phase
Uncontrolled malignancy or immunosuppressive therapy
Age under 18 years
Pregnancy or breastfeeding
Warnings
Use only under medical supervision.
Not a substitute for standard medical treatment of infections, autoimmune disorders, or immunodeficiency.
Monitor for signs of immune overstimulation (e.g., fever, rash, joint pain) during initial use.
Discontinue immediately and seek medical attention if unusual or severe symptoms occur.
Dosage & Administration
Subcutaneous injection only.
Low Dose (0.5 mg): 6 clicks daily- maintenance and general immune support (yields 40 doses)
Moderate Dose (1 mg): 12 clicks daily- moderate immune modulation and recovery support (yields 20 doses)
High Dose (2 mg): 24 clicks daily intensive immune restoration and targeted support (yields 10 doses)
Frequency: Once daily
Timing: Morning on an empty stomach or as directed by your healthcare provider
Administration Instructions
Wash hands and prepare a clean surface.
Attach a sterile needle.
Dial the required number of clicks.
Clean injection site (abdomen or upper thigh) with alcohol swab.
Insert needle at 45-90° angle and inject slowly.
Withdraw needle, dispose safely, and cap the pen.
Rotate injection sites to minimize irritation.
Always inspect solution before use: Do not inject if cloudy, discoloured, or containing particles.
Side Effects
Thymogen is generally well tolerated. Reported reactions are rare and mild, including:
Transient injection-site redness, itching, or mild swelling
Headache or light-headedness (usually resolves quickly)
Temporary fatigue or changes in energy levels during initial days
Rare mild flu-like symptoms (myalgia, low grade fever) during first week
If any severe or persistent symptoms occur, discontinue use and contact your healthcare provider immediately.
Storage & Handling
Store either in refrigerator (fridge); never freeze or in a cool dry place (≤25-30°C / 77-86°F).
Keep pen capped and protected from light and heat.
After first use: Same storage conditions.
Keep out of reach of children.
Discard if expired or solution appears abnormal.
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IMPORTANT NOTICE
This product is not intended to diagnose, treat, cure, or prevent any disease. Statements have not been evaluated by the FDA, SAHPRA, or other authorities. Always consult a licensed healthcare provider before use, especially if pregnant, breastfeeding, under 18, or managing medical conditions.
