HD Labs – Ozempic/Tirzepatide Hybrid – Trisema Pen 44mg
Semaglutide/Tirzepatide – Treat 2 diabetes and long-term weight management
Description
Trisema 44mg Pre Filled Pen is a cutting-edge injectable weight management compound combining two synergistic peptides in one formulation. Designed for once-weekly use, it delivers comprehensive metabolic support through improved blood glucose control, increased insulin sensitivity, and significant appetite suppression. The unique mechanism of action helps users feel fuller for longer, reduce caloric intake effortlessly, and enhance fat-burning potential while preserving lean muscle.
Ideal for individuals struggling with weight plateaus, insulin resistance, or persistent cravings, Trisema 44mg Pre Filled Pen is highly effective when paired with healthy nutrition and a consistent fitness routine. Its convenient pen delivery makes it easy to administer precise weekly doses with minimal hassle.
Benefits
Dramatically reduces appetite and food cravings
Supports rapid and sustained fat loss
Enhances insulin sensitivity and metabolic control
Slows gastric emptying for prolonged fullness
Aids body recomposition when paired with training
Easy-to-use weekly injection with click-based dosing
Loss of appetite (intentional, but may feel intense)
Dosages & Protocol
Dosing is administered in clicks on the pen. Titrate weekly as your body adjusts to the compound.
Suggested protocol – ONCE WEEKLY:
Week 1 – 4: 15 clicks (once weekly)
Week 5-8: 30 clicks
Week 9-12: 45 clicks
Week 13-16: 60 clicks
Cycle length: 12 to 24 weeks for optimal results
How to administer
Trisema 44mg Pre Filled Pen is injected subcutaneously once per week using the included pen and needles.
Steps:
Remove the cap and attach a new needle
Clean the injection site (abdomen or thigh)
Turn the dose dial to the correct number of clicks
Pinch the skin and insert needle at a 90° angle
Press the injection button and hold for 5–10 seconds
Remove the pen, dispose of the needle safely
Recap and store the pen in the fridge
Use a new needle for each injection. Rotate injection sites weekly.
Storage
Store refrigerated at 2–8°C
Do not freeze
Keep capped when not in use
Pen remains viable for up to 30 days after first use if refrigerated properly
HD MOTS-C 10MG VIAL
R 900
MOTS-C 10mg – HD Laboratories
MOTS-C is a mitochondrial-derived peptide (MDP) researched for its role in cellular energy regulation and metabolic signaling. Naturally encoded within mitochondrial DNA, MOTS-C functions as a metabolic messenger that helps regulate stress adaptation, glucose utilization, and mitochondrial efficiency.
The 10mg vial by HD Laboratories contains high-purity lyophilized MOTS-C intended for laboratory and research applications.
Mechanism of Action
MOTS-C is classified as a mitochondrial “mitokine” and primarily exerts its effects through metabolic signaling pathways:
AMPK Activation – Stimulates AMP-activated protein kinase, a key cellular energy sensor.
Enhanced Glucose Uptake – May promote improved glucose utilization at the cellular level.
Fatty Acid Oxidation Support – Encourages metabolic flexibility.
Nuclear Gene Regulation – Influences transcription factors associated with stress adaptation and metabolic balance.
Mitochondrial Efficiency – Supports cellular resilience under metabolic stress conditions.
Its mechanism makes it a peptide of interest in research related to metabolic health, body composition, endurance performance, and longevity pathways.
Potential Research Applications
While human clinical data remains limited, MOTS-C is commonly explored in research contexts for:
Metabolic optimization
Insulin sensitivity support
Body composition improvement
Exercise endurance and recovery
Healthy aging and mitochondrial support
All applications remain investigational.
Recommended Research Dosing Protocols
⚠ There are no FDA-approved or clinically established human dosing guidelines for MOTS-C. The following reflects commonly observed research practices and community protocols.
General Administration
Route: Subcutaneous (SC) injection
Typical Dose Range: 5–10mg per administration
Frequency: 2–3 times per week
Cycle Duration: 4–12 weeks
Break Period: 4–8 weeks off between cycles
Storage: Refrigerate at 2–8°C after reconstitution
Goal-Specific Protocol Examples
1. Metabolic Optimization
Dose: 5–10mg
Frequency: 2–3× weekly
Timing: Morning or before meals
Cycle: 8–12 weeks
Intended to align with circadian metabolic signaling and glucose regulation pathways.
2. Body Composition & Fat Oxidation
Dose: ~10mg per week (split into 2–3 injections)
Timing: 30–60 minutes before exercise
Cycle: 8–12 weeks
Often paired with structured nutrition and resistance training protocols.
3. Endurance & Athletic Performance
Dose: 10mg weekly (divided doses)
Timing: 30–60 minutes pre-workout
Cycle: 6–8 weeks
Explored for its interaction with exercise-induced AMPK activation.
4. Longevity & Mitochondrial Research
Dose: 5–10mg weekly
Frequency: 2× weekly
Cycle: 10–12+ weeks
Focuses on mitochondrial stress resilience and metabolic health pathways.
Timing Considerations
Morning administration may align with fasting metabolic activity.
Pre-workout dosing is often utilized to synergize with exercise-induced metabolic activation.
Consistency in weekly timing appears more important than exact hour of administration.
Administration Guidelines
Reconstitute with bacteriostatic water using sterile technique.
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring copper-binding peptide found in human plasma, saliva, and urine. It plays a vital role in tissue remodeling, collagen synthesis, and cellular repair. When levels decline with age, skin elasticity and regenerative capacity decrease — supplementing with GHK-Cu helps restore these functions. This peptide enhances fibroblast activity, promotes angiogenesis, and stimulates the synthesis of key extracellular matrix components such as collagen and elastin. Its benefits extend beyond cosmetic applications, also supporting wound repair, reducing inflammation, and strengthening hair follicles.
Benefits:
Stimulates collagen and elastin production for firmer skin
Promotes hair regrowth and scalp health
Accelerates wound healing and tissue regeneration
Reduces inflammation and oxidative stress
Improves skin tone, texture, and elasticity
Supports anti-aging and overall skin rejuvenation
Side Effects:
Mild skin irritation or redness at injection site
Temporary sensitivity or tingling sensation
Rare allergic reaction in sensitive individuals
Dosages & Protocol:
Beginners: 2mg injected subcutaneously once daily
Intermediate: 2mg injected twice daily (morning and evening)
Advanced: 2–4mg injected twice daily or applied topically for targeted repair
HD CAGRILINTIDE 10MG VIAL
R 1950
What Is Cagrilintide?
Type: Long-acting Amylin analogue
Developer: Novo Nordisk
Purpose: Appetite suppression & weight loss
Mechanism: Mimics amylin, a hormone that:
Slows gastric emptying
Increases satiety
Reduces hunger signals
Lowers food intake
It is not a GLP-1, but works extremely well together with GLP-1s.
🔥 Why It’s So Powerful
Cagrilintide is being developed mainly to be combined with Semaglutide (the combo is called CagriSema).
Studies show:
📉 Much stronger appetite suppression than Semaglutide alone
📉 Greater fat loss
🍽️ Dramatically reduced hunger and portion size
🧠 Less food noise and cravings
💪 Benefits
✅ Extreme appetite control
✅ Faster and more aggressive fat loss
✅ Better adherence to calorie deficit
✅ Works synergistically with:
Semaglutide
Tirzepatide
Retatrutide
HD SEMAGLUTIDE 10MG PEN
R2100
Introduction
Semaglutide 10mg is an advanced medication designed for weight management and diabetes control.
How It Works
Semaglutide works by mimicking a hormone that targets areas of the brain involved in appetite regulation.
Benefits
Enhances blood sugar control in type 2 diabetes patients.
Promotes significant weight loss.
Reduces risk factors associated with heart disease.
Usage
Primarily prescribed for managing type 2 diabetes and assisting in weight loss.
Recommended Dosage
Start with 0.25 mg once weekly.
Gradually increase to the effective dose of 6mg based on response and tolerability.
Conclusion
Semaglutide 10mg offers a dual benefit of diabetes control and weight reduction, making it a valuable treatment option.
HD SEMAGLUTIDE 10MG VIAL
R1600
Introduction
Semaglutide 10mg is an advanced medication designed for weight management and diabetes control.
How It Works
Semaglutide works by mimicking a hormone that targets areas of the brain involved in appetite regulation.
Benefits
Enhances blood sugar control in type 2 diabetes patients.
Promotes significant weight loss.
Reduces risk factors associated with heart disease.
Usage
Primarily prescribed for managing type 2 diabetes and assisting in weight loss.
Recommended Dosage
Start with 0.25 mg once weekly.
Gradually increase to the effective dose of 6mg based on response and tolerability.
Conclusion
Semaglutide 10mg offers a dual benefit of diabetes control and weight reduction, making it a valuable treatment option.
HD TIRZEPATIDE 30MG PEN
R 2600
Properties and Mechanism of Action
HD Labs Tirzepatide is a dual-agonist peptide that works by activating two key metabolic pathways:
GLP-1 receptor activation – promotes appetite suppression and improved satiety
GIP receptor activation – supports insulin sensitivity and efficient energy utilization
Supports metabolic balance – aids fat metabolism and overall metabolic function
Effects and Results Reduced appetite and cravings
Increased feelings of fullness and improved portion control
Enhanced fat metabolism and energy regulation
Support for healthy blood sugar levels and overall metabolic function
Results may vary depending on individual lifestyle, diet and exercise.
The HD Labs Tirzepatide Vial is administered via subcutaneous injection, typically once weekly.
Recommended guidance includes: Start with a low initial dose to support tolerability
Gradual dose escalation over several weeks
Maintain consistent weekly administration for best results
Possible Side Effects Some individuals may experience mild to moderate side effects, particularly during dose escalation:
Side effects are generally temporary and tend to subside as the body adjusts.
HD TIRZEPATIDE 30MG VIAL
R 2000
The HD Labs Tirzepatide Vial 30mg is a premium dual-agonist peptide therapy designed for advanced weight management, appetite control and metabolic optimization. Developed and formulated by HD Labs, this vial contains 30mg of Tirzepatide in a convenient format suitable for structured wellness and weight-loss programs. Tirzepatide targets both GLP-1 and GIP receptors, helping reduce cravings, improve satiety and enhance metabolic efficiency.
Properties and Mechanism of Action
HD Labs Tirzepatide is a dual-agonist peptide that works by activating two key metabolic pathways:
GLP-1 receptor activation – promotes appetite suppression and improved satiety
GIP receptor activation – supports insulin sensitivity and efficient energy utilization
Supports metabolic balance – aids fat metabolism and overall metabolic function
Effects and Results
Reduced appetite and cravings
Increased feelings of fullness and improved portion control
Enhanced fat metabolism and energy regulation
Support for healthy blood sugar levels and overall metabolic function
Results may vary depending on individual lifestyle, diet and exercise.
The HD Labs Tirzepatide Vial is administered via subcutaneous injection, typically once weekly.
Recommended guidance includes:
Start with a low initial dose to support tolerability
Gradual dose escalation over several weeks
Maintain consistent weekly administration for best results
Possible Side Effects
Some individuals may experience mild to moderate side effects, particularly during dose escalation:
Side effects are generally temporary and tend to subside as the body adjusts.
HD RETATRUTIDE 32MG PEN
R 2950
Premium High-Concentration Metabolic Therapy
HD Labs Retatrutide 32mg delivers an advanced, high-concentration formulation of this breakthrough triple-agonist peptide. Designed for experienced users seeking maximum efficacy, this pharmaceutical-grade vial provides enhanced dosing flexibility for comprehensive metabolic support and weight management goals.
Clinical Profile
Retatrutide represents the cutting edge in peptide-based metabolic therapy, simultaneously targeting GIP, GLP-1, and glucagon receptors. This triple-receptor mechanism provides comprehensive metabolic pathway activation, offering superior support for individuals committed to evidence-based weight management and body composition optimization.
Key Benefits
High-concentration 32mg formulation for extended treatment protocols
Enhanced dosing flexibility and cost-effectiveness.
Concentration: 32mg per vial
Form: Lyophilized powder for reconstitution
Manufacturer: HD Labs
Storage: Refrigerate at 2-8°C before and after reconstitution
Administration Guidelines
This product requires reconstitution with bacteriostatic water prior to subcutaneous administration. Due to the high concentration, precise dosing protocols must be established and monitored by a qualified healthcare professional with expertise in peptide therapy. Proper reconstitution technique and sterile handling are essential.
Quality Assurance
HD Labs maintains rigorous pharmaceutical manufacturing standards with comprehensive quality control testing for purity, potency, and sterility. Each vial includes complete batch traceability and certificate of analysis documentation.
Important: This product is intended for use under medical supervision by experienced individuals. Consult with a qualified healthcare provider before beginning any peptide therapy program. Not intended for use by individuals under 18 years of age or those new to peptide therapy.
HD RETATRUTIDE 32MG VIAL – R2500
Premium High-Concentration Metabolic Therapy
HD Labs Retatrutide 32mg delivers an advanced, high-concentration formulation of this breakthrough triple-agonist peptide. Designed for experienced users seeking maximum efficacy, this pharmaceutical-grade vial provides enhanced dosing flexibility for comprehensive metabolic support and weight management goals.
Clinical Profile
Retatrutide represents the cutting edge in peptide-based metabolic therapy, simultaneously targeting GIP, GLP-1, and glucagon receptors. This triple-receptor mechanism provides comprehensive metabolic pathway activation, offering superior support for individuals committed to evidence-based weight management and body composition optimization.
Key Benefits
High-concentration 32mg formulation for extended treatment protocols
Enhanced dosing flexibility and cost-effectiveness.
Concentration: 32mg per vial
Form: Lyophilized powder for reconstitution
Manufacturer: HD Labs
Storage: Refrigerate at 2-8°C before and after reconstitution
Administration Guidelines
This product requires reconstitution with bacteriostatic water prior to subcutaneous administration. Due to the high concentration, precise dosing protocols must be established and monitored by a qualified healthcare professional with expertise in peptide therapy. Proper reconstitution technique and sterile handling are essential.
Quality Assurance
HD Labs maintains rigorous pharmaceutical manufacturing standards with comprehensive quality control testing for purity, potency, and sterility. Each vial includes complete batch traceability and certificate of analysis documentation.
Important: This product is intended for use under medical supervision by experienced individuals. Consult with a qualified healthcare provider before beginning any peptide therapy program. Not intended for use by individuals under 18 years of age or those new to peptide therapy.
